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This clarifies why just one lorazepam dose, Regardless of its shorter serum half-daily life, has extra prolonged peak outcomes than an equivalent diazepam dose.[ninety nine] Lorazepam is swiftly conjugated at its 3-hydroxy team into lorazepam glucuronide which is then excreted inside the urine. Lorazepam glucuronide has no demonstrable CNS activity